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" ... Caffeine is known to block adenosine, which, in the brain, makes us sleepy. But in the heart, adenosine may be responsible for erratic heartbeat, so blocking it, the researchers say, could help stabilize heart rhythm. Or it may be the antioxidant properties of both the caffeine and the many polyphenols in coffee, which could reduce arrhythmias. ... "
" ... I don’t know about you, but over the course of my studies and my career, I have often relied caffeine and nicotine. (Although I quit smoking more than a decade ago and could not use them for my book). People have been using smokes and Joe to to promote mental focus since at least 600 BC. Caffeine blocks a brain chemical called adenosine that promotes sleep and suppresses arousal. Nicotine mimics the neurotransmitter acetylcholine, which causes brain cells in our sensory cortex and areas involved in attention to snap to life. ... "
" ... Start paying more attention to the levels of energy that everyone has in the afternoons, and consider avoiding afternoon meetings altogether. Educate your employees that as they drink coffee on a regular basis, their brain develops more adenosine receptors, so it will take more coffee to keep them awake. If they want to use caffeine to give them a needed boost, encourage them to use coffee strategically when they really need it. If your employees find they need a cup of coffee to give them that daily morning boost, encourage them to consider sleeping one hour more instead. ... "
" ... You may already know about the power of a short nap in the afternoon. That it can provide you with more energy and clearer thinking. Sleep does that by flushing out a brain-chemical that builds up after lots of brain activity called adenosine. Adenosine makes you feel tired, so the nap makes you feel refreshed. ... "