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" ... The result is severe pain and potential organ damage since your body parts are being deprived of oxygen. Stroke, vision loss, blood clots in the lungs, and infections are just some of the life-threatening complications that may result. Until now, there haven’t been any specific ways of preventing such crises, aside from drinking plenty of fluids and avoiding situations that may be triggers such as high elevation, extreme cold, physical exhaustion, and certain drugs like acetazolamide. Vaso-occlusive crises certainly can occur despite these precautionary measures. Treatment of such crises has mainly involved giving pain medications, hydration, oxygen, and potentially blood transfusions. ... "